Ingredients
Caffeine
The science behind using caffeine for the skin

What is Caffeine?
Caffeine is a heterocyclic alkaloid organic compound that is found in the seeds, nuts, and leaves of multiple plants native to South America and East Asia. As a skingredient, it can now be found in over 185 products including, but not limited to, facial moisturizers, scrubs, eye creams, anti-cellulite lotions, sunscreens, and tanning bronzers.
Credit: PubChem
What Does Caffeine Do?
Some common properties and functions of caffeine include…
Properties |
Functions |
Anti-aging/UV protectant |
Kills UV damaged skin cells, prevents the formation of precancerous cells, and sunburn lesions* that contribute to signs of aging |
Anti-cancer |
Protects against abnormal cell growth/damage from sun exposure ie: melanoma cancers |
Anti-cellulite |
Improves microcirculation, makes skin appear smoother and firmer to reduce the appearance of cellulite |
Anti-inflammatory |
Unknown mechanism may strengthen the anti-inflammatory response of immune cells |
Antioxidant |
Reduces harmful free radical formation to prevent cell and tissue damage |
Hair growth |
Improves hair cell barrier, stimulates the growth of follicle |
Vasoconstrictor |
Decreases blood flow to the skin, topical application cited to improve dark circles under eyes |
Potential Side Effects of Caffeine?
According to the Environmental Working Group Skin Deep database, caffeine is recognized as a generally safe low hazard ingredient. This may be due to the relatively low concentration of caffeine found in cosmetics, typically estimated around 3%. As a good rule of thumb, test new products on a skin patch prior to full use. Side effects of topical caffeine have not been vigorously discussed in reports, with findings including:
- Mild itching when used in patients with psoriasis vulgaris.
- Caffeine exposure in high concentrations may contribute to the aging process, as well as poor wound healing. High concentrations of caffeine caused a decrease in collagen synthesis in cultured skin cells in a 2014 study.
- Topical application may be more potent than originally thought. Scientists demonstrated exponential absorption of caffeine, particularly in skin with impaired barrier function.
The Buzz About Caffeine
It’s not just about skin-care, baggy eyes, and anti-cellulite. Caffeine is used as a hydrophilic model for testing how to make drug delivery more effective via the skin. Compounds such as nanoparticles and microemulsions ie: “permeation enhancers” are in development to better understand how to improve topical and transdermal application.
Practical Tips for Using Caffeine
- Pay attention to labels, and ask professionals. Your dermatologist is a great source for science-based research and formulas specific to your unique skin care
- Start small: test a new product with caffeine on a small area of skin prior to full use
- Avoid more sensitive parts of the skin, including under the eyes, face, or in particular dry/itchy areas.
- Take a before and after photo. Comparisons can better identify if a product is worth its value.
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* This Website is for general skin beauty, wellness, and health information only. This Website is not to be used as a substitute for medical advice, diagnosis or treatment of any health condition or problem. The information provided on this Website should never be used to disregard, delay, or refuse treatment or advice from a physician or a qualified health provider.
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